Peptide Hormone Secretion

In this the first of two volumes, attention is focused on procedures used in the isolation of polypeptide hormones and their indentification and structural analysis; the development of sensitive bioassay and immunoassay techniques; methods in current use for tissue localization of peptide hormones and their encoding MRNAs; and techniques for characterization of peptide hormone receptors. Wherever possible, the general principles and strategies on which the methods are based are given so that the techniques will have a wide application to biologically active peptides involved in neurotransmission, growth regulations, differentiation, and vasoregulation. This and the second volume "Peptide Hormone Action" are also published together as a two-volume set.