Lymphocyte Development: Cell Selection Events and Signals During Immune Ontogeny

"Lymphocyte Development" presents an extremely up-to-date account of

molecular processes involved in the development of lymphocytes. This

well written book is based on a graduate course taught by the author.

Topics include the selection processes involved in lymphocyte

maturation, immune receptor gene rearrangement, signaling pathways

involved in cell cycle progression and apoptosis, and the

transcriptional regulation of lymphoid ontogeny. The book also covers

T cell development and differentiation of helper and cytotoxic T cells

as well as the development of Natural Killer lymphocytes. The book

finishes with an account of the molecular basis of immunodeficiency

syndromes. It will interest researchers in immunology and it will be

useful as a supplementary text for a graduate level immunology

course.