Glucocorticoids

Following 50 years of glucocorticoid use in a clinical setting, an

international body of expert scientists and physicians presents the most

expansive survey of glucocorticoid pharmacology to date. This work

traces the history of glucocorticoid biology from the seminal

description of glucocorticoid insufficiency by Thomas Addison in the

mid-19th century, up to current advances in elucidating the molecular

basis of glucocorticoid action. Important discoveries are presented, as

well as milestones in drug development, a survey of current clinical

practice, and prospects for novel glucocorticoid-based therapeutics.

Scientists and clinicians will appreciate the scope of this work, which

is of special interest to workers in the fields of endocrinology,

inflammation and autoimmune disease.