Genomic Imprinting: Causes and Consequences

Originally published in 1995, this significant publication on genomic or parental imprinting was prepared by an outstanding team of international authorities. Genomic imprinting results in the preferential expression of one allele, depending on the parent of origin. It is associated with several disease syndromes in humans. Interest in this area has expanded rapidly from the time when it was first recognised that some aspects of inheritance were not adequately explained by the Mendelian laws. The chapters cover a wealth of material to help explain not only the mechanisms of genomic imprinting but also its biological and medical consequences. This interdisciplinary volume encompasses clinical genetics, pathology, developmental biology, evolution and genetics. It will be of interest to all scientists and clinicians working in this area.