Drg Stereochemistry Ana

Spanning research from Pasteur's initial separation of the tartaric acid enantiomers to the current marketing and clinical use of stereoisomeric drugs, this Third Edition contains new chapters on molecular chiral recognition, the use of enzymes for the synthesis and resolution of enantiomeric compounds, and the impact of stereochemistry on the ADMET stage of drug discovery, as well as revised and updated sections on chiral liquid and gas phase chromatography, stereoselective biotransformation, and protein binding. Documenting the explosion of advances in the field, this source analyzes transformations in the separation and pharmacological sciences and covers the latest issues regarding intellectual property, patenting, and national and international regulation.