Comparative Pharmacokinetics

This text presents an overview of pharmacokinetics. It explains the scientific data and mathematical models of the discipline within the context of biological reality. It uses a complete model of the field, from facts and constructs to clinical manifestations. Written for students, researchers, and comparative medicine clinicians, the book explains and assesses both mechanistic, compartmental models, and the newer empirical noncompartmental models, considering strengths and weaknesses of each. The text also explains establishment of appropriate parameters and proper collection and linking of data. Cross-referenced information provides multiple opportunities for study form a variety of perspectives and ultimately aids decision making. The book concludes with application of techniques to common problems.