Bacterial Superantigens: Structure, Function and Therapeutic Potential

This text focuses on three major aspects of bacterial superantigens. Firstly, it describes their crystal structure and characteristics; one chapter describes recent data on crystal structure of superantigens complexed with their receptor, the MHC class II molecule. Secondly, the book deals with the function and effects on the immune system of these molecules in vivo and in vitro. Finally, the text shows how their immunomodulatory properties in cancer therapy.